Hexamethyldisiloxane cas107-46-0 HMDO; HMDSO MM
HMDSO is used as an internal standard for calibrating chemical shift in H NMR spectroscopy. It is more easily handled since it is less volatile than the usual standard tetramethylsilane but still displays only a singlet near 0 ppm.
HMDSO has even poorer solvating power than alkanes. It is therefore sometimes employed to crystallize highly lipophilic compounds.
It is used in liquid bandages (spray on plasters) such as cavilon spray, to protect damaged skin from irritation from other bodily fluids. It is also used to soften and remove adhesive residues left by medical tape and bandages, without causing further skin irritation.
HMDSO is being studied for making low-k dielectric materials for the semi-conductor industries by plasma-enhanced chemical vapor deposition(PECVD).
HMDSO has been used as a reporter molecule to measure tissue oxygen tension (pO2). HMDSO is highly hydrophobic and exhibits high gas solubility, and hence strong nuclear magnetic resonance spin lattice relaxation rate (R1) response to changes in pO2. Molecular symmetry provides a single NMR signal. Following direct injection into tissues it has been used to generate maps of tumor and muscle oxygenation dynamics with respect to hyperoxic gas breathing challenge
Hexamethyldisiloxane cas107-46-0 HMDO; HMDSO MM
| Ecinces No. | 203-492-7 | ||
| Molecular Weight | 162.378 | ||
| Flash Point | 33 °F | ||
| Molecular Formula | C6H18OSi2 | ||
| Melting Point(℃) | ?59 °C | ||
| Density | 0.764 g/mL at 20 °C | ||
| Smiles | C[Si](C)(C)O[Si](C)(C)C | ||
| Appearance | Colorless Transparent Liquid | ||
| Note: |
Stability: hygroscopic
Safety: Hazardous – an additional Dangerous Goods freight charge may apply
Physical Characteristics: melting point -67°C, boiling point 101°C, density 0.764
